Human life there will always be unlimited for the reverie. Search for "eternal youth", there are 916,000 results; search for "longevity medicine", there are 2,510,000 results; search for "long life", very, be up to 305,000,000.

Recently, the American scientists in the "Nature" magazine that a drug adriamycin名叫雷帕may be able to extend the human life span. The compound was born in the 20th century, 70s, Easter Island in Chile by soil micro-organisms found in a product.

Let the magic drug Yeonsu mice 30%

University of Texas researchers in the United States with nearly 2000 to about 600 days of age in the mouse experiments, these the life span of the mouse equivalent of human 60-year-old. The researchers used mice in the three-quarters of rapamycin, and other normal fed rats, the experimental results for comparison. It was found that female mice rapamycin so that the longest life expectancy from 1245 days to 1094 days, so that the longest life span of male mice from the 1179 days to 1078 days.

experimental drug from the beginning of the day count, drug so that life expectancy of female mice 38%, so that life expectancy of male rats 28%, on the whole life to make the mouse 9-14%.

researchers of different ages were compared experimental mice. If the mice from the young to start taking it more obvious Yeonsu effect. Strangely enough, these 600 days have been a young rats, the drug can also happen in their role.兰迪斯特朗members of the research team said: "We believe that this is the first convincing evidence that people can slow down the aging process, more older people in the use of drug therapy can extend life expectancy."

in clinical treatment, as rapamycin, can inhibit the propagation of immune cells, it often used to prevent organ transplantation when rejection, before the study shows these drugs have been able to extend the yeast , line worms, fruit flies and other invertebrates of life, but found that it can effectively extend the life span of mammals, also is the first time.

Yeonsu Why has the effect of rapamycin? U.S. scientists found that the body can inhibit the biological protein target of rapamycin (mTOR) generation. Under normal circumstances, mTOR can help cells to create new proteins, promote cell reproduction, growth and differentiation. These processes involved in the fruit fly, nematode, yeast and mammalian aging, and people are likely to have a similar impact, but the regulation of mTOR in the life of the precise role is still unclear, so the role of rapamycin mechanism is still a mystery. In addition, some experts speculated that rapamycin may inhibit some age-related reproductive cells, or slow down the metabolism, such as.

the aging of the U.S. National Institute of intervention in the pilot scheme, a systematic assessment of the anti-aging drug candidates in mice after the effect of that rapamycin is selected to show the success of the first effects of the drug Yeonsu . Paul United States, Harvard Medical School - Grant of biological aging mechanism of the laboratory of David Sinclair believes that this finding is exciting, and perhaps it will be a milestone for the future development of drugs specified in the right direction.

obvious side effects, cost very expensive

when we cheered for this discovery, some people are not so optimistic, experimental participants Richard E m Rene said: "If some people think that these experimental data to develop life-prolonging elixir elixir of life, increasing life expectancy of 10-20 years, or an average of 30%, and that he was very irresponsible." Now this can not be found clinical trials, because rapamycin interfere with the side effects of the immune system so that people taking the drug is vulnerable to risk of infection, the experiment in mice can be sterile environment, and people can not. In addition, rapamycin also increased the probability of the body infected with a virus-induced cancer and may be after some sort of "improvement" only allow human use. Guangdong Provincial People's Hospital medical director of heart doctors Jin-jun said: "rapamycin has many medical uses, such as blood vessels, such as dredging, but if the use of healthy people may cause anemia and other diseases."

from animal experiments to clinical trials still have a long way to go, in accordance with past practice, the animal experimental data on the response in the body are often unstable, in which up to 90% of animal experiments is not safe for people. So, it is necessary to overcome the side effects of rapamycin and come up with new drugs and, through clinical trials, market sales, at least more than 10 years.

dosage is also a problem, the medical use of rapamycin for the daily dose is usually 2 mg to 5 mg, and the mice taking a daily dose of up to 2.24 mg per kilogram of body weight, in order to maintain with the effect of blood levels of rapamycin required for the large number of 50 kg, for example, 100 mg daily dose in order to maintain efficacy Yeonsu experiment, and now, the United States market, the retail price of rapamycin 100 mg per 525 U.S. dollars, and China, about 100 mg 2,500 yuan, which will be scattered and the daughter of a day of money.

And, as the British "Daily Mail" comments, and perhaps drugs can make people live longer, but it may not be able to make from being in old age, vision, hearing, such as reduced pain and even dementia. And more social problems will also be followed, such as the aging of the population, housing, social welfare.