A study showed that newly emerged North American Type A new strain of H1N1 influenza virus genes of all influenza viruses from pigs, but from two different lineages, one of the swine influenza virus lineage about 10 years ago people, poultry, swine influenza virus heterozygotes.

China Animal Health and Epidemiology Center陈继明such as researchers, with the Internet database platform for influenza virus, swine influenza virus of a pedigree analysis, and got the above findings. The results were published in "Science Bulletin" in 2009 on No. 12.

North America for the emerging new type of influenza virus H1N1 strain (hereinafter referred to as the new North American strain) the source of much controversy in the academic community. Some experts believe that it is a special "heterozygote", containing the pig from the North American, European and Asian pigs, poultry and human influenza virus gene sequences, this view prompted the new virus has little to do with the pigs. Some scholars believe that the new North American strain of all gene fragments from the swine flu virus, this view of this new virus closely related with the pig.

"not all come from a human influenza virus, and in some cases can be directly infected swine influenza virus; not all those who continue the evolution of influenza virus is still a human influenza virus, they can divide the swine flu virus, which was originally a human influenza virus infection in pigs, the adoption of certain point mutations, to obtain the adaptive capacity of pigs, which are widespread in swine herds in the few infected people go, so they will no longer be a human influenza virus but swine flu virus. "陈继明in the July 6 to accept the" Science Times "interview, explained the characteristics of influenza virus ecology and evolution.

陈继明group of influenza viruses in GenBank with web-based database platform "Influenza Virus Resource", on a different host from the various genes of influenza virus PB1 gene in particular, a more comprehensive analysis of the lineage found in North America new strain of NA and MP gene from a lineage of swine influenza virus, the HA, NP, NS, PB1, PB2 and PA gene from another lineage of influenza viruses. The previous pedigree was 30 years ago, the origin of the avian flu virus; after a pedigree of 10 years ago in the form of people, pigs, avian influenza virus heterozygotes - the PB2 and PA genes from avian influenza virus, PB1 genes Since the human H3N2 influenza virus subtypes, including H3N2 subtype of human influenza virus PB1 gene in 1968, about the origin of the avian flu virus.

Recently, the "Nature" (Nature) published a monthly magazine 6 Guan, such as the University of Hong Kong people are the result of the virus source. Its conclusions as follows: North America is a new strain of swine influenza virus from 2 of the genetic recombination and the formation, and the 2 swine influenza virus in swine popular among at least 10 years.

Guan Study Group pointed out that the variation of influenza viruses capable of reorganization, control swine flu epidemic of great significance. The pandemic is due to the absence of inter-swine influenza virus surveillance system, which led to the existence of the virus has been evolving and have a chance to stop.

Guan previously in an interview with the media, said: "The conclusion to the source of a virus, the most scientific method is to track the source genome." According to Guan, the laboratory he started in 1976 from influenza surveillance program has been collecting a lot of samples, set up a database of influenza.

In order to answer these two sources of the North American strain of the new group is starting from genomic research, but the views of the other issues are not the same. Guan Yi believes that this strain is the formation of natural evolution, rather than from a laboratory.

this,陈继明said: "In the laboratory, the use of reverse genetic manipulation technology, man-made North America a new strain of influenza to engage in global research in many laboratories, not a difficult task, but can not leave any traces of manual operation; In other words, man-made and naturally occurring virus, the virus is no different, therefore, existing information can not be ruled out in North America of a new strain from the laboratory may be. "

, however, two research groups that, in view of the prevalence of this virus in recent days the situation, this virus will spread further spread of the global, long-term presence in the crowd and, possibly, in the prevalence of swine, swine need to be closely monitored .

陈继明Study Group pointed out that the new strain in North America in the world after the wide dissemination of the scope, it could lead to the original H1N1 human influenza A H3N2 subtype of influenza or influenza virus disappeared.

"The fast spread of the virus in domestic large-scale dissemination is a matter of time before, so many people now concerned about the vaccine production and supply. "陈继明but suggested that the vaccine should be used with caution because in the past more than three months, the accumulation of a large number of epidemiological data shows that the new strain in North America itself is not toxic , and its destruction or even weaker than seasonal influenza, a vaccine and any of the drugs have some side effects.