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According to Taiwan's "United Evening News" reported that the Taiwan Ocean University, Taiwan University of Science and Technology "Central study Home "Genome Research Center, hands out R & D to see the world's first DNA vaccine patch, vaccination a major breakthrough in the way, the future of the people do not have to Hospital were vaccinated, the vaccine only at home patch attached to the arm, we can achieve prevention disease the effect is faster in 2012, the slowest six to ten years can be listed. to participate in this study Taiwan Ocean University food WU Zhang Zhe, associate professor of Science, said the type of vaccine hours of traditional vaccines and biotechnology two major categories of vaccines, DNA vaccine is a DNA vaccine. DNA vaccine immunization means the principal, usually by intramuscular injection or gene gun, such as the DNA into the body, but will inevitably be painful intramuscular injection, the number of children and adults have the so-called "needle fear", and an estimated 100 times for each injection China will take place 5 times a serious injection injuries. the World Health Organization (WHO) estimates that hepatitis B virus infection, hepatitis C virus and AIDS drug cases, respectively, 32%, 40% and 5% are caused by improper use of the injection. As though the use of gene gun DNA volume less, but the high cost of related equipment, and technical production of the vaccine threshold bullets high, not universal. WU Zhang-chul said, DNA is larger than the protein molecules, it is difficult to penetrate the skin into the body; even if reluctantly into the body, but also easy to DNA enzyme (DNase) broken down. They use micro-body with positively charged lipid, DNA characteristics negatively to Lipsome body coated with the DNA vaccine, one to overcome the limitations, the DNA vaccine into the body. WU Zhang-chul said that the skin surface of the cuticle, will block a lot of things from outside, so as long as the first through the acid to remove the stratum corneum, the body-coated Liposome DNA vaccines can be transmission into the body through skin. Micro-lipid membrane and the structure of similar skin is phospholipid bilayer, micro fat body cell membrane can be combined easily into the skin cell DNA vaccine which showed the vaccine antigen, activate the immune response, to the effect of prevention of disease . research team is currently being developed for Japanese encephalitis virus DNA vaccine patch is expected to amount to the island's biotechnology industry, the next pandemic will be North Korea sexy to run virus, enterovirus, dengue , avian influenza and SARS, such as DNA vaccine patch efforts. WU Zhang-chul said, DNA vaccine patch fairly stable at room temperature can be preserved, and any affixed to each part of the arm, and then affixed to a three-week, two immune effect can occur. Pain due to the convenience and is available to all their operations at home, the market potential.
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